HTMwire
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Sepio

Network Monitoring

HTMwire assessment

Sepio provides hardware-based asset visibility through AssetDNA, a layer-1 physical-layer fingerprinting technology that identifies and validates every connected device. The approach detects rogue, spoofed, and hidden hardware threats across networks, supporting zero trust hardware security.

Key Features

  • AssetDNA layer-1 hardware fingerprinting
  • Rogue and spoofed device detection
  • Hardware asset visibility
  • Zero trust hardware security

What Sets Them Apart

Layer-1 physical-layer hardware fingerprinting (AssetDNA) detects rogue and spoofed devices that traffic-based tools miss.

How Sepio Uses AI

No AI/ML

HTMwire's independent read on the technology — not the vendor's marketing claim.

Tags

hardware-security asset-visibility rogue-device-detection zero-trust network-monitoring

Frequently Asked Questions

What is Sepio used for?

Sepio provides hardware-based asset visibility through AssetDNA, a layer-1 physical-layer fingerprinting technology that identifies and validates every connected device. It detects rogue, spoofed, and hidden hardware threats across networks to support zero trust hardware security.

What makes Sepio different?

Sepio's differentiator is layer-1 physical-layer hardware fingerprinting (AssetDNA), which detects rogue and spoofed devices that traffic-based tools miss. The company was founded in 2017 and is based in Rockville, MD.

Does Sepio use AI?

No, Sepio does not market an AI or ML capability. Its AssetDNA technology is based on layer-1 physical-layer hardware fingerprinting rather than machine learning.

Sources

  1. Sepio — AssetDNA layer-1 hardware fingerprinting and rogue device detection

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Last updated: June 8, 2026